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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS6
All Species:
17.88
Human Site:
Y106
Identified Species:
39.33
UniProt:
Q7L5N1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5N1
NP_006824.2
327
36163
Y106
I
I
D
K
E
Y
Y
Y
T
K
E
E
Q
F
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100125
326
36044
Y105
I
I
D
K
E
Y
Y
Y
T
K
E
E
Q
F
K
Dog
Lupus familis
XP_536866
321
35704
Y100
I
I
D
K
E
Y
Y
Y
T
K
E
E
Q
F
K
Cat
Felis silvestris
Mouse
Mus musculus
O88545
324
35862
Y103
I
I
D
K
E
Y
Y
Y
T
K
E
E
Q
F
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NUC2
318
35518
Y97
T
I
N
K
E
Y
Y
Y
T
K
E
E
Q
F
K
Zebra Danio
Brachydanio rerio
NP_001017768
297
33615
K87
E
Q
F
K
Q
V
F
K
E
M
E
F
L
G
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCY3
341
38287
N119
V
I
N
K
D
Y
Y
N
K
K
E
Q
Q
Y
K
Honey Bee
Apis mellifera
XP_393678
338
37998
N116
I
I
D
R
D
Y
Y
N
T
K
E
E
Q
F
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192086
297
33638
K87
E
Q
F
K
Q
V
F
K
D
H
E
F
L
G
W
Poplar Tree
Populus trichocarpa
XP_002330530
306
34249
F93
Q
E
L
Y
K
K
V
F
P
H
F
Y
I
L
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W206
317
35640
K96
D
R
S
F
L
E
K
K
Q
E
L
Y
K
K
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99
97.5
N.A.
97.8
N.A.
N.A.
N.A.
N.A.
88.6
83.7
N.A.
56.8
62.7
N.A.
70
Protein Similarity:
100
N.A.
99
97.8
N.A.
98.4
N.A.
N.A.
N.A.
N.A.
93.8
87.7
N.A.
75
76.3
N.A.
80.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
86.6
13.3
N.A.
53.3
80
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
93.3
26.6
N.A.
86.6
93.3
N.A.
26.6
Percent
Protein Identity:
35.4
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
56.8
N.A.
N.A.
56.5
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
46
0
19
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
19
10
0
0
46
10
0
0
10
10
82
55
0
0
0
% E
% Phe:
0
0
19
10
0
0
19
10
0
0
10
19
0
55
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
10
% G
% His:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% H
% Ile:
46
64
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
73
10
10
10
28
10
64
0
0
10
10
64
% K
% Leu:
0
0
10
0
10
0
0
0
0
0
10
0
19
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
19
0
0
0
0
19
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
10
19
0
0
19
0
0
0
10
0
0
10
64
0
0
% Q
% Arg:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
55
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
19
10
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% W
% Tyr:
0
0
0
10
0
64
64
46
0
0
0
19
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _